Beadle and Ephrussi's Transplantation Technique for Drosophila

Boris Ephrussi (1901-1979)

Boris Ephrussi studied fruit flies, yeast, and mouse [3] genetics and development while working in France and the US during the twentieth century. In yeast, Ephrussi studied how mutations in the cytoplasm persisted across generations. In mice he studied the genetics of hybrids and the development of cancer. Working with George Wells Beadle [4] on the causes of different eye colors in fruit flie...

Specific Reactions of the Ovary to Interspecific Transplantation among Members of the Melanogaster Group of Drosophila.

HE transplantation of ovaries in Drosophila was realized for the first T time by EPHRUSSI and BEADLE (1935b), using the technique which they had devised and applied with such success to the transplantation of the eye discs and other anlagen. Their results showed that the ovaries of D. melamguster can be successfully implanted into male and female larvae of the same species, can become attached ...

Malpighian Tubes as Sources of Diffusible Substances Development of Eye Colors in Drosophila: Fat Bodies

The Development of Eye Colors in Drosophila Melanogaster. Further Studies on the Mutant Claret.

HESE studies were undertaken in order to repeat and supplement T the experiments of BEADLE and EPHRUSSI (1936,1937) and EPHRUSS~ and BEADLE (1936b) which provided the evidence upon which these authors postulated the existence of ca+ substance as one of three specific diffusible substances assumed to be necessary for the differentiation of wild type eye color in Drosophila melanogaster. The firs...

Development of Eye Colors in Drosophila: Diffusible Substances and Their Interrelations.

N EXPERIMENTS reported in a series of papers by the authors an I attempt has been made to attack various problems concerned with eye color development in Drosophila melanogaster by the use of the technique of transplantation. These experiments have led to the elaboration of a scheme bearing on one phase of the general problem of the relation of genes to eye color development. Evidence has been ...